Patient Rights

Presentations

Case Studies

Clinical Trials

Radiology

Archives

Physician Referral

Patient Registration

Comments

ICDO
International
Castlemans
Disease
Organization

European Journal of Pediatrics

Abstract Volume 155 Issue 12 (1996) pp 1015-1017

Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease

T. A. De Heer-Groen (1), A. B. J. Prakken (3), N. M. A. Bax (3), P. J. van Dijken (2)

(1) Hospital Centre Apeldoorn, The Netherlands
(2) Riyadh Armed Forces Hospital, Kingdom of Saudi Arabia
(3) University Hospital for Children and Youth, `Het Wilhelmina Kinderziekenhuis\', P. O. BOX 18009, 3501 CA Utrecht, The Netherlands Tel.: 31(0)30-2320625 Fax: 31(0)30-2320712

Received: 10 February 1996 Accepted: 23 March 1996

Abstract We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely.

Conclusion Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.

Key words Castleman disease · Microcytic anaemia · Childhood

 BACK

DISCLAIMER:

CASTLEMAN's DISEASE HOMEPAGE is provided for educational purposes only. Consult your own physician regarding the applicability of any opinions or recommendations with respect to your symptoms or medical condition.

* CASTLEMAN's DISEASE HOMEPAGE is intended as a reference for health care professionals. The authors and editors have used sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication.

Medical knowledge changes rapidly. In view of the possibility of human error or changes in medical science, neither the authors, the editors, St. Vincent Hospital, nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they are not responsible for any errors or omissions or for the results obtained from the use of such information. Readers are encouraged to confirm the information contained herein with other sources.